Peter W Schiller Selected Research

Morphine (MS Contin)

1/2016	Bifunctional Peptide-Based Opioid Agonist-Nociceptin Antagonist Ligands for Dual Treatment of Acute and Neuropathic Pain.
12/2015	Dual Alleviation of Acute and Neuropathic Pain by Fused Opioid Agonist-Neurokinin 1 Antagonist Peptidomimetics.
11/2015	The bifunctional μ opioid agonist/antioxidant [Dmt(1)]DALDA is a superior analgesic in an animal model of complex regional pain syndrome-type i.
3/2015	Synthesis and biological evaluation of compact, conformationally constrained bifunctional opioid agonist - neurokinin-1 antagonist peptidomimetics.
11/2012	Superior analgesic effect of H-Dmt-D-Arg-Phe-Lys-NH2 ([Dmt1]DALDA), a multifunctional opioid peptide, compared to morphine in a rat model of neuropathic pain.
1/2009	Differential analgesic effects of a mu-opioid peptide, [Dmt(1)]DALDA, and morphine.
3/2005	Differential respiratory effects of [Dmt1]DALDA and morphine in mice.

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Peter W Schiller Research Topics

Disease

9	Tics (Tic) 03/2015 - 05/2005
7	Neuralgia (Stump Neuralgia) 01/2018 - 11/2012
5	Pain (Aches) 01/2019 - 04/2008
3	Hyperalgesia 01/2023 - 11/2012
2	Peripheral Nervous System Diseases (PNS Diseases) 01/2023 - 01/2018
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2018 - 11/2011
2	Acute Pain 10/2017 - 01/2009
2	Respiratory Insufficiency (Respiratory Failure) 01/2016 - 03/2005
2	Cocaine-Related Disorders (Cocaine Addiction) 04/2014 - 09/2013
1	Neoplasms (Cancer) 01/2023
1	Colonic Neoplasms (Colon Cancer) 01/2018
1	Hypersensitivity (Allergy) 10/2017
1	Body Weight (Weight, Body) 01/2016
1	Chronic Pain 01/2016
1	Ischemia 11/2015
1	Reflex Sympathetic Dystrophy (Reflex Sympathetic Dystrophy Syndrome) 11/2015
1	Weight Gain 10/2014
1	Obesity 10/2014
1	Heart Diseases (Heart Disease) 10/2011
1	Cardiomyopathies (Cardiomyopathy) 10/2011
1	Sepsis (Septicemia) 03/2010
1	Hypoxia (Hypoxemia) 03/2005
1	Myocardial Stunning (Stunned Myocardium) 08/2004
1	Reperfusion Injury 08/2004

Drug/Important Bio-Agent (IBA)

10	Peptides (Polypeptides)IBA 01/2023 - 08/2004
10	Opioid Analgesics (Opioids)IBA 10/2017 - 01/2009
10	Analgesics (Analgesic Drugs)IBA 10/2017 - 04/2008
7	Morphine (MS Contin)FDA LinkGeneric 01/2016 - 03/2005
6	Carboxylic AcidsIBA 09/2013 - 10/2005
5	2',6'- dimethyltyrosyl- arginyl- phenylalanyl- lysinamideIBA 11/2015 - 03/2005
5	1,2,3,4-tetrahydroisoquinolineIBA 09/2013 - 10/2005
5	Opioid Peptides (Opioid Peptide)IBA 11/2012 - 03/2005
4	tyrosyl- 1,2,3,4- tetrahydro- 3- isoquinolinecarbonyl- phenylalanyl- phenylalanine (TIPP)IBA 09/2013 - 01/2007
3	AntioxidantsIBA 01/2016 - 08/2004
3	LigandsIBA 01/2016 - 04/2011
3	Phenylalanine (L-Phenylalanine)FDA Link 03/2012 - 11/2009
2	tyrosyl-arginyl-phenylalanyl-lysinamide (DALDA)IBA 01/2019 - 11/2012
2	Substance PIBA 10/2017 - 04/2011
2	Prorenin ReceptorIBA 01/2016 - 10/2014
2	Nonesterified Fatty Acids (NEFA)IBA 01/2016 - 10/2011
2	phenylalanylphenylalanineIBA 09/2013 - 10/2005
2	Narcotic Antagonists (Opioid Antagonists)IBA 03/2012 - 11/2009
2	hydroxide ionIBA 02/2012 - 11/2009
2	cyclohexylalanineIBA 02/2012 - 01/2007
2	delta Opioid Receptors (delta Opioid Receptor)IBA 11/2009 - 10/2005
1	Antineoplastic Agents (Antineoplastics)IBA 01/2023
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2023
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2018
1	NociceptinIBA 01/2016
1	CarbohydratesIBA 01/2016
1	Triglycerides (Triacylglycerol)IBA 01/2016
1	PeptidomimeticsIBA 12/2015
1	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2015
1	prostaglandin-inositol cyclic phosphateIBA 11/2015
1	Acetylcysteine (Siran)FDA LinkGeneric 11/2015
1	Insulin (Novolin)FDA Link 10/2014
1	ReninIBA 10/2014
1	A 19IBA 10/2014
1	2- tyrosyl- 1,2,3,4- tetrahydroisoquinoline- 3- carboxylic acidIBA 09/2013
1	2',6'- dimethyltyrosyl- 1,2,3,4- tetrahydroisoquinoline- 3- carboxylic acidIBA 02/2012
1	Opioid Receptors (Opioid Receptor)IBA 01/2012
1	MicroRNAs (MicroRNA)IBA 10/2011
1	Aromatic Amino Acids (Aromatic Amino Acid)IBA 04/2011
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2010
1	LipopolysaccharidesIBA 03/2010
1	DipeptidesIBA 11/2009
1	1,2-dibromo-3-chloropropane (DBCP)IBA 11/2009
1	morphiceptinIBA 04/2008
1	Amino Acids FDA Link 01/2007
1	1,3-di(4-imidazolinophenoxyl)propaneIBA 10/2005
1	mu Opioid Receptors (mu Opioid Receptor)IBA 05/2005
1	Naloxone (Narcan)FDA LinkGeneric 03/2005

Therapy/Procedure

2	Drug Therapy (Chemotherapy) 01/2023 - 01/2018
2	Therapeutics 10/2014 - 11/2011
1	Ligation 11/2012
1	Analgesia 03/2005